Kallikreins, kinins and cardiovascular diseases: a short review.
نویسنده
چکیده
Studies of kallikrein-kinin systems since the 1930's have now led to substantial insight into the importance of this vasoactive system in the regulation of cardiovascular and renal function. It now seems clear that before long, these insights will lead to new therapeutic attacks upon diseases of the cardiovascular system and kidneys. This survey of notable recent work also emphasizes the fact that few of these fascinating new findings would have been produced without the stimulus of the initial discoveries of Héctor R Croxatto.
منابع مشابه
Biochemical, Pharmacological, and Functional Aspects of Glandular Kallikreins
Kallikrein (EC 3.4.21.8) specifies those serine proteinases which liberate kinins from kininogens by limited proteolysis and have no or only little proteolytic activity on other proteins (for review, see refs. 2,3,21). Unfortunately, this definition fits two totally different groups of proteinases: the glandular, tissue or organ kallikreins on the one hand, and the plasma or serum kallikrein on...
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عنوان ژورنال:
- Biological research
دوره 31 3 شماره
صفحات -
تاریخ انتشار 1998